Figure 8: CTMP suppression increases cisplatin cytotoxicity in HNSCC cells. | Scientific Reports

Figure 8: CTMP suppression increases cisplatin cytotoxicity in HNSCC cells.

From: Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation

Figure 8

Following exposure of the indicated cells to various concentrations of cisplatin for 24 h, cell viability was measured using a WST-1 proliferation assay. Although the cell lines were resistant to cisplatin treatment, CTMP siRNA-transfected cells demonstrated marked cisplatin-induced cytotoxic effects compared with control siRNA-transfected cells. Data represent the means ± SD of three independent experiments. NS, not significant; *P < 0.05; **P < 0.01; ***P < 0.001.

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