Table 1 Anti-tumor activity of the samples against S-180 tumor grown in BLAB/c mice.

From: Anti-tumor effect of β-glucan from Lentinus edodes and the underlying mechanism

Samples

Dose (mgkg−1day−1)

Days

Inhibition ratio (%)

Enhancement ratio of body weight (%)

Spleen index (%)

Thymus index (%)

Control

 

10

 

97.47 ± 1.39

8.87 ± 1.59

1.07 ± 0.083

Cytoxan

20

10

54 ± 8.10a

90.88 ± 0.97

5.47 ± 1.26a

0.44 ± 0.56a

LNT

1

10

75 ± 1.53a,b

100.85 ± 0.00

8.43 ± 2.06

1.08 ± 0.427

 

5

10

59 ± 9.13a

100.59 ± 0.89

9.02 ± 1.64

0.94 ± 0.194

 

20

10

68 ± 7.44a

103.66 ± 0.03

9.62 ± 1.09

1.42 ± 0.252

  1. Mice were injected with S-180 cells (3.0 × 106 cells/animal s.c.). The animals were treated with the samples, after tumor implantation for 24 h, for ten consecutive days. Data are presented as mean ± SD of ten animals.
  2. ap < 0.05 compared with Control group by ANOVA followed by student’s t-test.
  3. bp < 0.05 compared with Cytoxan group by ANOVA followed by student’s t-test.
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