Figure 7 | Scientific Reports

Figure 7

From: Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide

Figure 7

Knockdown of DHC2 expression in 2 different primary GBM cell lines.

(a) Western blot. Cells were grown and transfected with two different siRNAs for 8 h and cultured for 48 h and then subjected to Western blot analysis of protein expressions. The graph is the summarized data of the blot. *P < 0.05; **P < 0.01. (b) Changes in viability of cells after knockdown of DHC2 expression followed by temozolomide treatment for one week. Cells were then counted and the graph showed the number of survival cells in different groups (#P > 0.05; *P < 0.05; and **P < 0.01).

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