Figure 3
From: Highly Multiplexed RNA Aptamer Selection using a Microplate-based Microcolumn Device
Binding analysis of candidate aptamer sequences.
(a) Measurement of dissociation constants for aptamers to 5 different protein targets by EMSA experiments. The data were fitted to the Hill Equation to determine the KD. (b) A list of the dissociation constants for all of the aptamer candidates tested and their multiplicity ranking in their respective final (R4C4) pools. A complete list of the top 3,000 aptamer clusters for final pools of each target is provided in Supplementary Dataset 1.
