Table 3 Effect of overexpression of hpaBC on L-DOPA production*.

From: Genome engineering Escherichia coli for L-DOPA overproduction from glucose

Strain

OD600

Tyrosine (mg/L)

L-DOPA (mg/L)

E. coli DOPA-30 (pQE30)

4.87 ± 0.06

462.7 ± 7.0

210.2 ± 6.9

E. coli DOPA-30(pQE30-2hpaBC)

7.10 ± 0.15

546.8 ± 10.4

490.3 ± 8.3

E. coli DOPA-30 (pQE30-phaBCN)

5.08 ± 0.02

0.0 ± 0.0

650.3 ± 23.6

E. coli DOPA-30N

4.87 ± 0.06

0.0 ± 0.0

614.3 ± 19.1

  1. *Experiments were conducted in triplicates and measurements are presented with their means and s.d.