Table 4 L-DOPA production in different microorganisms.

From: Genome engineering Escherichia coli for L-DOPA overproduction from glucose

Microorganism

Substrate

Enzyme

L-DOPA (g/L)

Reference

Acremonium rutilum

tyrosine

Tyrosinase

0.89

2

Aspergillus oryzae

tyrosine

Tyrosinase

1.69

3,4

Yarrowia lipolytica NRRL-I43

tyrosine

Tyrosinase

2.96

5

Bacillus sp. JPJ

tyrosine

Tyrosinase

0.5

6

Brevundimonas sp. SGJ

tyrosine

Tyrosinase

3.81

7,8

E. coli

glucose

Tyrosinase

0.293

15

Erwinia herbicola

catechole, pyruvate

Tpl

11.1 g/L/h

9

E. coli

catechole, pyruvate

Tpl

20.7

10

E. coli

catechole, pyruvate

Tpl

29.8

12

Pseudomonas aeruginosa

catechole, pyruvate

Tpl

2.76

13

E. coli

tyrosine

PHAH

9.47

14

E. coli

glucose

PHAH

1.51

16

E. coli DOPA-30N

glucose

PHAH

8.67

This study

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