Figure 2: Histological assessment and oxidative stress level 24 h after focal cerebral I/R injury following Sesn2 silencing in rats. | Scientific Reports

Figure 2: Histological assessment and oxidative stress level 24 h after focal cerebral I/R injury following Sesn2 silencing in rats.

From: Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats

Figure 2

(A) Representative HE staining and Nissl staining in the cortex (×400). (B) Areas about HE and Nissl staining (in the box). (C) Histograms showing quantification of intact neurons in the cortex. (D) SOD activity was lower in the Sesn2 siRNA group than in the MCAO group. (E) Histograms showing that MDA levels in the Sesn2 siRNA group were significantly higher than in the MCAO group. Scale bars = 50 μm. Error bars represent mean ± SEM. (**p < 0.01; ***p < 0.001). n = 4 in the sham group, n = 6 in the other groups.

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