Figure 1
From: Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice
Polysome formation is decreased in the fat body and gut of dilp2-3,5 mutants.
(a) Representative polysome profiles of isolated 10 day old Drosophila tissues. Insets show the area under the curve measurements for monosomes and combined polysomes. Unpaired student t-test was used to establish significance. *p < 0.05 (n = 4). (b) Relative 35S counts in dilp2-3,5 mutants for thoraces (n = 17), fat bodies (n = 37) and guts (n = 37). Values were first normalized by protein content, then to batch average. Outliers were removed based on the Grubbs test, unpaired student t-test was used to establish significance. *p < 0.05.
