Table 3 Lipoprotein subfractions in CAD participants according to ages.

From: HDL subfractions and very early CAD: novel findings from untreated patients in a Chinese cohort

 

Very early

Early

Late

p value

n = 81

n = 304

n = 349

Lipid parameters

    

TG (mg/dL)

191.2 ± 105.0

176.0 ± 112.4

152.5 ± 85.1

0.001

TC (mg/dL)

193.3 ± 42.5

192.7 ± 41.8

182.5 ± 36.1

0.002

HDL-C (mg/dL)

36.80 ± 7.87

41.82 ± 12.45

43.01 ± 13.58

<0.001

LDL-C (mg/dL)

127.42 ± 42.02

128.56 ± 38.05

118.94 ± 34.25

0.001

HDL subfraction

    

Large HDL (mg/dL)

10.16 ± 4.31

12.47 ± 6.23

14.34 ± 7.30

<0.001

Medium HDL (mg/dL)

19.01 ± 3.93

20.75 ± 6.57

21.01 ± 6.44

0.035

Small HDL (mg/dL)

8.10 ± 3.74

8.35 ± 3.33

8.01 ± 3.29

0.435

Large HDL (%)

26.77 ± 7.52

29.10 ± 8.03

32.04 ± 7.99

<0.001

Medium HDL (%)

51.42 ± 5.58

50.04 ± 5.17

48.95 ± 4.80

<0.001

Small HDL (%)

21.75 ± 7.47

20.63 ± 7.54

18.95 ± 6.22

<0.001

LDL subfraction

    

Large LDL (mg/dL)

27.70 ± 9.52

26.87 ± 10.65

27.11 ± 8.46

0.846

Medium LDL (mg/dL)

22.24 ± 9.23

20.77 ± 8.95

19.20 ± 8.98

0.039

Small LDL (mg/dL)

10.80 ± 12.41

10.27 ± 10.00

7.45 ± 8.33

0.003

Large LDL (%)

14.49 ± 4.46

13.86 ± 4.23

14.75 ± 3.90

0.076

Medium LDL (%)

11.14 ± 3.12

10.50 ± 3.24

10.13 ± 3.70

0.130

Small LDL (%)

4.99 ± 4.97

5.02 ± 4.51

3.79 ± 3.93

0.008

Mean LDL particle size (Å)

265.54 ± 6.13

265.42 ± 5.93

267.03 ± 5.54

0.011

  1. Data are expressed as mean ± SD. The bold values indicated statistical significance. TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein.