Table 4 Relation of lipoprotein subfraction with prevalent of very early CAD.

From: HDL subfractions and very early CAD: novel findings from untreated patients in a Chinese cohort

 

Late

Early

p value

Very early

p value

Unadjusted analysis

HDL subfraction (mg/dL)

Large HDL

1

0.958 (0.934–0.982)

0.001

0.872 (0.825–0.922)

<0.001

Medium HDL

1

0.994 (0.970–1.018)

0.604

0.935 (0.889–0.983)

0.008

Small HDL

1

1.030 (0.984–1.079)

0.203

1.008 (0.937–1.086)

0.827

LDL subfraction (mg/dL)

Large LDL

1

0.997 (0.977–1.017)

0.743

1.006 (0.976–1.037)

0.682

Medium LDL

1

1.021 (0.999–1.043)

0.057

1.037 (1.005–1.071)

0.024

Small LDL

1

1.033 (1.012–1.055)

0.002

1.038 (1.008–1.069)

0.013

Mean LDL particle size (Å)

1

0.951 (0.919–0.983)

0.003

0.955 (0.908–1.004)

0.072

Adjusted analysis

HDL subfraction (mg/dL)

Large HDL (mg/dL)

1

0.933 (0.905–0.961)

<0.001

0.899 (0.848–0.954)

<0.001

Medium HDL (mg/dL)

1

0.985 (0.959–1.012)

0.274

0.956 (0.908–1.007)

0.091

Small HDL (mg/dL)

1

1.015 (0.966–1.067)

0.552

0.992 (0.918–1.072)

0.839

LDL subfraction (mg/dL)

Large LDL

1

0.989 (0.968–1.011)

0.335

1.001 (0.968–1.036)

0.940

Medium LDL

1

1.012 (0.988–1.037)

0.327

1.014 (0.979–1.051)

0.425

Small LDL

1

1.028 (1.005–1.052)

0.016

1.021 (0.990–1.054)

0.184

Mean LDL particle size (Å)

1

0.954 (0.920–0.990)

0.012

0.973 (0.921–1.028)

0.323

  1. Logistic regression analysis was applied. The bold values indicated statistical significance. HDL, high-density lipoprotein; LDL, low-density lipoprotein. The adjusted covariates included sex, BMI, hypertension, dyslipidemia, DM, current smoking and family history of CAD.