Table 2 IC50 of α-KPA.

From: Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues

Time (min) from start

0.17 mM

0.3 mM

1 mM

2 mM

10

21

21

21

61

20

21

21

21

61

30

21

21

21

71

40

31

31

31

81

50

41

41

41

91

60

51

51

51

101

  1. Inhibition of Mtb-rDapA in the presence of 400 μM of ASA and variable concentrations of pyruvate.
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