Table 4 Univariate analysis of factors associated with disease-specific survival in the acral melanoma cohort.
From: Acral Melanoma in Chinese: A Clinicopathological and Prognostic Study of 142 cases
Characteristics | No. Pts | No. of DOD (%) | P value* |
|---|---|---|---|
All patients | 142 | 83 (58.5) | |
Sex | |||
Male | 84 | 48 (57.1) | |
Female | 58 | 35 (60.3) | 0.512 |
Age, years | |||
<55 | 41 | 26 (63.4) | |
≥55 | 101 | 57 (56.4) | 0.732 |
Trauma history | |||
Yes | 8 | 5 (62.5) | |
No | 134 | 78 (58.2) | 0.486 |
Longest diameter of lesion, cm | |||
≤2 | 72 | 42 (58.3) | |
>2 | 70 | 41 (58.6) | 0.492 |
Duration of the lesion, years | |||
≤2.5 | 88 | 61 (69.3) | |
>2.5 | 54 | 22 (40.7) | <0.001 |
Site of lesion | |||
Nonungual location | 119 | 68 (57.1) | |
Subungual location | 23 | 15 (65.2) | 0.895 |
Histologic subtype | |||
ALM | 122 | 67 (54.9) | |
Other | 20 | 16 (80.0) | 0.081 |
Breslow thickness, mm | |||
≤4.0 | 83 | 35 (42.2) | |
>4.0 | 59 | 48 (81.4) | <0.001 |
Clark level | |||
I/II/III | 14 | 2 (14.3) | |
IV/V | 128 | 81 (63.3) | 0.009 |
Ulceration | |||
Yes | 68 | 54 (79.4) | |
No | 74 | 29 (39.2) | <0.001 |
Mitotic rate, mm−2 | |||
≤15 | 131 | 73 (55.7) | |
>15 | 11 | 10 (90.9) | <0.001 |
TILs | |||
Absent | 46 | 21 (45.7) | |
Present | 96 | 62 (64.6) | 0.155 |
Vascular invasion | |||
Absent | 139 | 80 (57.6) | |
Present | 3 | 3 (100.0) | 0.002 |
Regional lymph node metastasis at diagnosis | |||
Yes | 46 | 39 (84.8) | |
No | 96 | 44 (45.8) | <0.001 |
Pathologic stage | |||
0/I | 20 | 1 (5.0) | |
II/III/IV | 122 | 82 (67.2) | <0.001 |
