Table 3 Allelic distribution of HLA class II alleles and their correlation with HCV infection outcome in Chinese population.

From: The Associations of HLA-A*02:01 and DRB1*11:01 with Hepatitis C Virus Spontaneous Clearance Are Independent of IL28B in the Chinese Population

HLA allele

Spontaneous clearance n (%)

Persistent infection n (%)

P (Pc)

OR (95%C.I.)

DPB1*02:01

73 (16.1)

145 (17.0)

0.914

0.983 (0.716, 1.349)

DPB1*02:02

24 (5.3)

52 (6.1)

0.671

0.897 (0.543, 1.482)

DPB1*04:01

39 (8.6)

70 (8.2)

0.643

1.103 (0.728, 1.671)

DPB1*05:01

178 (39.2)

340 (39.8)

0.695

1.053 (0.812, 1.367)

DPB1*13:01

29 (6.4)

65 (7.6)

0.527

0.862 (0.545, 1.364)

DQB1*02:01

31 (6.7)

60 (7.0)

0.651

0.901 (0.573, 1.417)

DQB1*02:02

33 (7.2)

38 (4.4)

0.063

1.576 (0.972, 2.557)

DQB1*03:01

121 (26.3)

167 (19.5)

0.017 (0.136)

1.398 (1.060, 1.843)

DQB1*03:02

27 (5.9)

46 (5.4)

0.892

1.035 (0.633, 1.693)

DQB1*03:03

77 (16.7)

126 (14.7)

0.579

1.093 (0.798, 1.499)

DQB1*05:02

38 (8.3)

113 (13.2)

0.002 (0.016)

0.547 (0.370, 0.809)

DQB1*06:01

41 (8.9)

84 (9.8)

0.394

0.842 (0.567, 1.251)

DQB1*06:02

22 (4.8)

52 (6.1)

0.227

0.729 (0.436, 1.220)

DRB1*03:01

31 (6.7)

60 (7.0)

0.626

0.893 (0.565, 1.410)

DRB1*04:05

16 (3.5)

52 (6.1)

0.022 (0.176)

0.514 (0.288, 0.916)

DRB1*07:01

35 (7.6)

47 (5.5)

0.214

1.338 (0.844, 2.120)

DRB1*08:03

23 (5.0)

44 (5.1)

0.715

0.907 (0.537, 1.531)

DRB1*09:01

77 (16.7)

117 (13.6)

0.281

1.197 (0.863, 1.659)

DRB1*11:01

44 (9.5)

45 (5.2)

0.007 (0.056)

1.820 (1.172, 2.826)

DRB1*12:02

56 (12.1)

96 (11.2)

0.9

1.024 (0.713, 1.470)

DRB1*15:01

43 (9.3)

107 (12.5)

0.031 (0.248)

0.657 (0.448, 0.964)

  1. Alleles with >5% frequencies are shown at the 4-digit level and analyzed; Pc, Corrected P value for multiple comparisons by Bonferroni correction. Alleles with statistical significance after Bonferroni correction are indicated in bold.