Figure 4
From: Microbial Cryptotopes are Prominent Targets of B-cell Immunity
Analysis of cryptotope indices for different viral and bacterial pathogens.
Human immune sera were probed for reactivity with common infectious pathogens (CMV, human Cytomegalovirus (n = 109); RSV, respiratory syncytial virus (n = 139); H1N1, influenza virus strain H1N1 (n = 139); S. aureus, Staphylococcus aureus strain MRSA CCUG 26215 (agr1) (n = 150); E. coli, Escherichia coli strain JM109 (n = 150)) under native (Tris) and denaturing (Urea) conditions. Bars indicate the median CI of all sera evaluated and error bars indicate the IQR. Volumes of serum samples were not sufficient in 11 patients to be tested also in the RSV and H1N1 assay.
