Table 3 Adjusted means of heart rate variability (HRV) indices presented by NPY genotype and PSS score.

From: Association of neuropeptide Y promoter polymorphism (rs16147) with perceived stress and cardiac vagal outflow in humans

HRV index

a Low-PSS group (n = 601)

p †

a High-PSS group (n = 522)

p †

b Post hoc comparisons

C/C (n = 301)

C/T (n = 236)

T/T (n = 64)

C/C (n = 230)

C/T (n = 234)

T/T (n = 58)

LF

5.87 ± 0.06

5.85 ± 0.07

5.96 ± 0.13

0.73

6.02 ± 0.07

6.11 ± 0.06

6.29 ± 0.13

0.16

 

HF

5.38 ± 0.06

5.38 ± 0.06

5.36 ± 0.12

0.81

5.43 ± 0.06

5.61 ± 0.06

5.80 ± 0.12

0.013

C/C<T/T*

LF/HF

0.50 ± 0.06

0.46 ± 0.07

0.59 ± 0.12

0.67

0.59 ± 0.06

0.50 ± 0.06

0.48 ± 0.12

0.49

 

RMSSD

3.46 ± 0.03

3.43 ± 0.03

3.44 ± 0.06

0.80

3.46 ± 0.03

3.55 ± 0.03

3.65 ± 0.06

0.020

C/C<T/T*

  1. Data are presented as mean ± standard error.
  2. aLow- and high-PSS groups were determined by a median split at PSS score 21.
  3. bBonferroni correction was applied to the post hoc testing.
  4. †Adjusted for the covariates listed in Table 2 (variables associated with individual HRV indices were all entered as covariates in ANCOVA models with the corresponding index as a dependent variable).
  5. Abbreviations: PSS, Perceived Stress Scale; LF, low frequency power [ln(ms2)]; HF, high frequency power [ln(ms2)]; LF/HF, ratio of LF to HF [ln(ratio)]; RMSSD, the root mean square of successive heartbeat interval differences [ln(ms)].
  6. *p < 0.05.
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