Figure 1
From: Factors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis
Vascular remodeling is accelerated by suture removal.
(a) Reversible suture-induced inflammatory corneal neovascularisation model used for the study. (b) Serial slit lamp images of suture IN and suture OUT arms. (c) Corresonding vascular density quantified from slit lamp images. For density quantification, n = 4 and asterisk represents p-value < 0.05 between suture OUT and IN. Error bars represent standard error of the mean (SEM). (d,e) Whole-mount dual immunofluorescence for CD31 and Collagen IV in suture OUT and suture IN, respectively. (f) Comparison between suture OUT and suture IN at both 24 and 120 h revealed delayed basement membrane deposition in suture OUT and continued active sprouting with suture IN.
