Figure 4: Effects of BPA exposure on dendritic spine density and morphology alteration.

(A) Representative 10 μm dendritic shaft with spines of hippocampal neurons. The changes of dendritic spine density (/10 μm) (B) and the percentage of mushroom shaped spines (C) in CA1 pyramidal neuron and DG granule neuron in male and female rats (*p < 0.05, **p < 0.01, ***P < 0.001). N =6 or 7 rats and n = 30∼35 neurons per group.