Table 1 Gene expression changes in EMT process of differentiating ESCs compared to ESCs.
Gene symbol | Day 6 | Day 10 | Gene symbol | Day 6 | Day 10 | Gene symbol | Day 6 | Day 10 |
|---|---|---|---|---|---|---|---|---|
CDH1 | −1.3 | −9.5 | TWIST1 | −1.7 | −1.5 | SNAI1 | 1 | −1.1 |
CDH2 | 2.4 | 6.1 | TWIST2 | 1.2 | 1.1 | |||
ZEB1 | 3.1 | 23.8 | SNAI2 | 4.7 | 4.5 | |||
Epithelial-specific genes known to be repressed by ZEB1 | ||||||||
Tight junction | Desmosomes and epidermis | Cell surface receptors | ||||||
OCLN | −1.2 | −1.8 | PPL | −1.2 | −4.6 | CD24 | −1.5 | −4.8 |
CLDN7 | −2.1 | −6.6 | DSG2 | −1 | −2.5 | Vesicle transport | ||
F11R | 1.3 | −1.7 | EPPK1 | 1.1 | −2.9 | TMEM30B | −1.8 | −11.4 |
MARVELD2 | 1 | −2.3 | SH3YL1 | −1.5 | −2.4 | MAL2 | −1.6 | −6.7 |
Cell polarity | DMKN | −1.3 | −3.9 | |||||
CRB3 | −1.1 | −1.6 | ||||||
