Figure 4

Impact of MDM2 SNP55 and 309 on age at colon cancer diagnosis.
(A) Cumulative percentage of individuals with colon cancer diagnosis as a function of age, among SNP55 T-allele carriers (TT and TC genotypes combined; red triangles) compared to non-T-allele carriers (CC genotype; blue diamonds). (B) Cumulative percentage of individuals with colon cancer diagnosis as a function of age, among SNP55 T-allele carriers (TT and TC genotypes combined; red triangles) compared to non-T-allele carriers (CC genotype; blue diamonds), restricted to individuals harbouring the MDM2 SNP309 T-allele (TG and TT genotypes).