Figure 6
From: Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination
Angiogenesis is an active process in TB patients.
(a) ELISA testing for VEGF in serum from healthy blood donors (control, n = 8), contacts (n = 7) and TB patients (n = 17). (b) PBMC isolated from contacts (n = 11) and from TB patients (n = 9) were stained for CD31 and CD45 (upper two panels). Expression of CD34 and VEGFR-2 was analyzed in cells from R2 (lower two panels). (c) Percentage of EPCs for each contact or patient was quantified by flow cytometry. *P < 0.05, **P < 0.01, and ***P < 0.001.
