Figure 6 | Scientific Reports

Figure 6

From: Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy

Figure 6

Bexarotene treatment increases the levels of autophagy markers LC3B-II and p62 in P301L-Tau neuronal cells.

(A) Representative Western blots showing expression of LC3B, p62 and beclin-1 after 24 h treatment of N2A cells with 0.5 μM bexarotene. (B) Densitometry results of autophagy markers after normalization to β-actin. Paired t-test against Ctrl, LC3B TG p = 0.005, p62 TG p = 0.023 N = 6/group. *p < 0.05, **p < 0.01.

Back to article page