Figure 2

24 h mean arterial pressure, heart rate and locomotor activity across the 4-week water restriction protocol: (a) 24-hour average mean arterial pressure (MAP), (b) heart rate and (c) locomotor activity in control (
) and water-restricted (
) SHR at baseline and across the 4-week protocol of water restriction. All data are presented as mean ± SEM. Data were analyzed using repeated-measures ANOVA with Bonferroni’s post-hoc tests (28 comparisons). No correction was made for sphericity. **P ≤ 0.01 versus baseline (3-day average). n = 6–9 per group.