Figure 4: LTBP1 N-terminus displays calcium-dependent binding to heparin which promotes oligomerization. | Scientific Reports

Figure 4: LTBP1 N-terminus displays calcium-dependent binding to heparin which promotes oligomerization.

From: Independent multimerization of Latent TGFβ Binding Protein-1 stabilized by cross-linking and enhanced by heparan sulfate

Figure 4: LTBP1 N-terminus displays calcium-dependent binding to heparin which promotes oligomerization.

(A) Biacore analysis of 50 nM NT1 binding to immobilized heparin dp-20 in the presence of calcium (green) or 5 mM EGTA (red). (B) AUC analysis of NT1 in the absence (blue) and presence of heparin (black) showing increased propensity to form higher order oligomers.

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