Table 2 Results of the inhibition of one-pot assay by D-Cycloserine, Compound 3 and Compound 4 against Mur Enzymes from Mtb.

From: Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis

  1. Residual activities (RAs) were calculated with respect to ‘no drug’ control assays (containing 5% DMSO) at 100 μM concentration. The IC50 was determined by measuring the activity at six different compound concentrations (5, 10, 25, 50, 75, 100 μM) and represents the concentration for which the RA was 50%.
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