Figure 6
From: Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation
Thapsigargin and TRAIL co-treatment regulate the ROS generation, NADPH oxidase activity, Caspase 3 activity, Caspase 9 activity, and GSH levels in human ESCC cells (24 h).
(A) ROS concentrations are shown. (B) NADPH oxidase activity is shown. (C) The intracellular Caspase 3 activity levels are shown. (D) The intracellular Caspase 9 activity levels are shown. (E) Intracellular GSH levels are shown. The three indexes in the control group were defined as 100%. The results are expressed as the mean ± SD; n = 6. aP < 0.05 vs. the control group in EC109 cells, abP < 0.05 vs. the control group in TE12 cells.
