Figure 1 | Scientific Reports

Figure 1

From: Loss of interleukin 33 expression in colonic crypts - a potential marker for disease remission in ulcerative colitis

Figure 1

Expression of mucosal IL33 is increased in acute ulcerative colitis.

Panel (a) shows an increase in mucosal mRNA expression for selected cytokines from colonic biopsies comparing acute ulcerative colitis (n = 29) with a healthy control group (n = 21). Panel (b) shows the same cytokine profile for patients with ulcerative colitis (n = 29) with a pairwise comparison of biopsies taken during active disease and at disease remission. No change was detected for IL33, IL1RL1 and IL4 (p > 0.05). Results for (a,b) are given as fold change (2−∆∆CT) with mean values, and the upper limit of the 95% confidence interval as error bars. Statistical analysis was performed using Mann U Whitney Test (a) and Wilcoxon Signed Ranks Test (b) with *p-value < 0.01, **p-value < 0.001 shown in panels. Panels (c) and (d) show individual values of relative gene expression (2−∆CT) of IL33 and IL1RL1, respectively, for acute disease and normal controls, with the horizontal line representing the median value.

Back to article page