Figure 4

The correlation between CD4⁺ T cell subsets and CD19⁺ B cell subsets in IBCa.

(A) The positive correlation was found between the percentages of CD4⁺ T cells and CD19⁺ B cells (r = 0.397, P < 0.001). (B) The positive correlation was found between CD4⁺CD25⁺CD127^low/− Tregs and CD19⁺CD24⁺CD38⁺ Bregs (r = 0.316, P = 0.001). (C) The positive correlation was found between PD-L1⁺ Bregs and Bregs (r = 0.267, P = 0.007). (D) The positive correlation was found between PD-L1⁺ Bregs and CD4⁺CD25⁺CD127^low/− Tregs (r = 0.299, P = 0.003). (E) There was significantly negative correlation between PD-L1⁺ Bregs vs PD-1^hi CD4⁺ CD25⁺ CD127⁺ effector T cells (r = −0.220, P = 0.031).