Table 4 Top disease predictions for rosiglitazone from the server.

From: DPDR-CPI, a server that predicts Drug Positioning and Drug Repositioning via Chemical-Protein Interactome

Rank

Disease

Confidence

1

251: Other disorders of pancreatic internal secretion

0.95

 251.2: Hypoglycemia, unspecified

0.83

2

250: Diabetes mellitus

0.93

 250.1: Diabetes with ketoacidosis

0.93

 250.10: Diabetes with ketoacidosis, type ii or unspecified type, not stated as uncontrolled

0.93

 250.01: Diabetes mellitus without mention of complication, type i [juvenile type], not stated as uncontrolled

0.89

 250.00: Diabetes mellitus without mention of complication, type ii or unspecified type, not stated as uncontrolled

0.81

 250: Diabetes mellitus

0.80

3

362: Other retinal disorders

0.91

 362.83: Retinal edema

0.73

 362.10: Background retinopathy, unspecified

0.62

 362.9: Unspecified retinal disorder

0.62

4

277: Other and unspecified disorders of metabolism

0.87

 277.85: Disorders of fatty acid oxidation

0.81

5

276: Disorders of fluid electrolyte and acid-base balance

0.87

 276.2: Acidosis

0.87

 276.69: Other fluid overload

0.64

6

365: Glaucoma

0.85

 365: Glaucoma

0.85

 365.9: Unspecified glaucoma

0.85

 365.1: Open-angle glaucoma

0.84

 365.10: Open-angle glaucoma, unspecified

0.84

 365.13: Pigmentary open-angle glaucoma

0.84

 365.04: Ocular hypertension

0.84

 365.00: Preglaucoma, unspecified

0.82

7

331: Other cerebral degenerations

0.83

 331.0: Alzheimer’s disease

0.82

  1. The diseases are grouped into ICD-9 families and ranked by their confidence values.