Figure 1 | Scientific Reports

Figure 1

From: Mesenchymal stem cells with Sirt1 overexpression suppress breast tumor growth via chemokine-dependent natural killer cells recruitment

Figure 1

The effect of MSCs with Sirt1 overexpression on breast cancer tumor growth in mice.

(A) The tumor growth were detected per 3 days after subcutaneous administration with 4T1 cells. The width and length of 4T1 tumors were measured, then the volume of tumor was calculated using the formula: volume = width2  × length × 0.5236. (B) Tumor weights were measured after they were harvested from the mice. (C) Tumors were presented by representive photographs. Each group consists of 5 mice. *, p < 0.05; **, p < 0.01. MSCs-GFP, MSCs with GFP overexpression; MSCs-Sirt1, MSCs with Sirt1 overexpression.

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