Table 2 Calcium signaling pathway and its association with LAD and LVA using two enrichment tools.

From: Genomic contributors to atrial electroanatomical remodeling and atrial fibrillation progression: Pathway enrichment analysis of GWAS data

Enrichment tool

Phenotype

C

O

E

R

rawP

adjP

WebGestalt

LAD

177

85

27.12

3.13

1.2E-24

2.7E-22

 

LVA

 

70

23.5

2.98

2.4E-18

5.5E-16

GATHER

LAD

196

88

  

4.0E-05

5.2E-03

 

LVA

 

73

  

1.2E-04

1.5E-02

  1. C, the number of reference genes in the category; O, the number of genes in the gene set and also in the category; E, expected number in the category; R, the ratio of enrichment, rawP, the p value from hypergeometric test (Webgestalt) or Fisher’s exact test (GATHER); adjP, the p value adjusted by the multiple test adjustment. Please note that GATHER does not provide E and R.
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