Table 2 Algorithm used for mTRG Published grading guidelines used for scoring all specimens (n = 52).

From: Assessment of pathological response to therapy using lipid mass spectrometry imaging

mTRG

MSI lipid signature profile

Area viable tumor + UN (%)

Area fibrosis + inflammation (%)

1

0

0–100

2

<7*

0–100

3

≥7 and <50

≥50

4

≥50

≥5

5

≥50

0–5

  1. *7% was used as cutoff point to correlate with ‘rare’ tumor foci by a clinical pathologist.
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