Figure 1
From: Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
TBN attenuates brain infarct volume and improves neurological function in monkeys subjected to t-MCAo.
(A) Representative images of T2-weighted MRI scan. (B,C) Brain infarct size of ipsilateral hemisphere. Data were expressed as dot plots with means in the left panel and mean ± s.e.m. in the right panel (n = 6 for each group). (D) Success rate of food catching of the contralateral, stroke-affected hand. Data were expressed as mean ± s.e.m. (n = 6 for each group). ‘@3 h’ and ‘@6 h’ mean TBN treatment initiating at 3 h and 6 h post-ischemia.
