Table 4 Predicted CTL epitopes from the ZIKV E protein.

From: Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins

Residue number

Peptide sequence

Predicted MHC binding affinity

Rescale binding affinity

C-terminal cleavage affinity

Transport affinity

Prediction score*

MHC ligand

53

MAEVRSYCY

0.4403

1.8696

0.9649

3.021

2.1654

Yes

85

QSDTQYVCK

0.2076

0.8813

0.5921

0.443

0.9922

Yes

129

SIQPENLEY

0.4389

1.8634

0.9329

3.175

2.1621

Yes

159

ETDENRAKV

0.1722

0.7311

0.9755

−0.11

0.872

Yes

195

GLDFSDLYY

0.6604

2.8041

0.7805

2.599

3.0511

Yes

198

FSDLYYLTM

0.5872

2.4933

0.9307

−0.065

2.6297

Yes

205

TMNNKHWLV

0.2026

0.8603

0.9214

0.369

1.0169

Yes

308

CTAAFTFTK

0.1876

0.7964

0.6855

0.467

0.9226

Yes

324

GTVTVEVQY

0.1984

0.8423

0.9769

2.779

1.1278

Yes

368

STENSKMML

0.2251

0.9558

0.9741

0.675

1.1357

Yes

  1. *Prediction score threshold was set at >0.75000. Bold indicates amino acids that were also predicted as antigenic sites.
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