Table 7 Characteristics of the study population (Validation Study).

From: Circulating long-non coding RNAs as biomarkers of left ventricular diastolic function and remodelling in patients with well-controlled type 2 diabetes

Variable

Type 2 diabetes Patients

N = 30

Age (years)

55.0 ± 5.7

Time since diagnosis of diabetes (years)

4.3 ± 2.9

Body mass index (kg/m2)

28.0 ± 3.3

Waist circumference (cm)

101.1 ± 10.2

Subcutaneous fat volume (mL)

648.7 ± 272.6

Visceral fat volume (mL)

422.8 ± 207.8

Systolic blood pressure (mm Hg)

126.9 ± 11.0

Diastolic blood pressure (mmHg)

75.4 ± 8.6

Heart rate (bpm)

64.9 ± 9.4

Concomitant medication N (%)

 Statin

12 (40.0)

 Any antihypertensive medication

13 (43.3)

 β-Blocker

1 (3.3)

 Diuretic

1 (3.3)

 ACE inhibitor

8 (26.7)

 ARB

4 (13.3)

 Calcium antagonist

1 (3.3)

HbA1c (%)

7.0 ± 1.0

Plasma fasting glucose (mmol/L)

7.8 ± 1.3

Plasma fasting insulin (pmol/L)

79.7 ± 45.6

Total cholesterol (mmol/L)

4.9 ± 1.2

LDL cholesterol (mmol/L)

2.8 ± 0.8

HDL cholesterol (mmol/L)

1.1 ± 0.3

Plasma triglycerides (mmol/L)

2.3 ± 2.8

Plasma NEFA (mmol/L)

0.5 ± 0.2

us-CRP (mg/L)

12.8 ± 29.3

NT-proBNP (ng/L)

30.9 ± 21.7

Parameters of cardiac dimensions and function

 LV mass (g)

106.1 ± 14.3

 LV end-systolic volume (mL)

65.5 ± 14.8

 LV end-diastolic volume (mL)

157.6 ± 25.1

 LVMV-ratio (g/mL)

0.7 ± 0.1

 LV Stroke volume (mL)

92.2 ± 14.5

 LV Ejection Fraction (%)

58.6 ± 5.1

 Cardiac index (L/min * m−2)

2789.9 ± 438.8

 E peak filling rate (mL/s)

412.1 ± 82.3

 E-decpeak (mL/s2*10−3)

−3.4 ± 1.0

 E-decmean (mL/s2*10−3)

−2.2 ± 0.7

 E/A peak flow

1.1 ± 0.3

 E/Ea

10.6 ± 4.6

 Neutral lipid content (%)

0.8 ± 0.5

  1. Data are presented as mean ± SD for continuous variables and as frequencies (percentages) for categorical variables. *Statistically significant. ACE: Angiotensin-converting enzyme; ARB: angiotensin receptor blocker; HbA1c: Glycated haemoglobin. For other abbreviations see the text.