Table 1 Baseline characteristics of the study population.

From: Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI

Profile

Folic acid group (n = 84)

Control group (n = 84)

P-valuea

Demographics

 Age at screening (years)

73.71 ± 2.57

73.52 ± 3.03

0.77

 Female

57 (67.86)

58 (69.05)

0.43

 Total education (years)

9.14 ± 3.53

9.81 ± 3.09

0.15

Lifestyle

 Smoker—ever

51 (60.71)

53 (63.10)

0.19

 Alcohol (units/week)

9.09 ± 9.11

8.51 ± 8.33

0.13

 Systolic BP (mmHg)

145 ± 22

147 ± 24

0.66

 Diastolic BP (mmHg)

82 ± 11

81 ± 10

0.54

 BMI (kg/m2)

24.53 ± 3.79

25.01 ± 4.11

0.17

Medical history

 Diabetes mellitus—ever

5 (5.95)

4 (4.76)

0.13

 Hypertension

6 (7.14)

7 (8.33)

0.64

 Vascular disease

11 (13.10)

10 (11.90)

0.24

MMSE

25.60 ± 2.22

26.13 ± 2.51

0.33

Folate (ng/mL)

7.01 ± 1.01

6.33 ± 0.97

0.44

Hcy (mmol/L)

13.65 ± 4.82

12.19 ± 3.85

0.57

Vitamin B12(pg/mL)

571.25 ± 23.37

568.48 ± 16.33

0.46

  1. Results are shown as n (%) for the chi-square or Fisher’s exact tests and as the mean ± SD for independent t-tests (two-tailed). aP < 0.01: significant difference between groups. Abbreviations: BP, blood pressure; BMI, Body Mass Index; Hcy, homocysteine.
Back to article page