Figure 1
From: A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation
The incorporation of BrdU in the colon of naïve WT and Spred2 KO mice.
Colons were harvested from naïve WT or Spred2 KO mice 2 hours after intra-peritoneal injection of BrdU (50 μg/g body weight). (a) Photos of H&E staining of the distal portion of colon tissues from untreated WT or Spred2 KO mice are shown. (b) The incorporation of BrdU was examined by immunohistochemistry. Representative results from four animals are shown (original scale bar, 100 μm). (c) The incorporation of BrdU in colonic epithelial cells of WT and Spred2 KO mice was quantitated and presented as BrdU labeling index. Data is presented as the mean ± SEM. ***p < 0.0001. n = 4.
