Table 1 Clinical characteristics of DM1 and control patients.
From: Validation of plasma microRNAs as biomarkers for myotonic dystrophy type 1
Clinical Characteristics | DM1, n = 103 | CTR, n = 111 |
|---|---|---|
Age at sampling (average ± se) | 44.1 ± 1.3 | 43.0 ± 1.0 |
Age of onset (average ± se) | 25.9 ± 1.3 | NR |
Sex (male/female) | 58/45 | 51/60 |
MRC megascore (average ± se) | 118.6 ± 1.9 | 150.0 ± 0.0 |
Myotonia (% of patients) | 87 | 0 |
Glucose (normal values: 70–110 mg/dl) | 88.7 ± 1.2 | 90.3 ± 1.3 |
Cholesterol (normal values: <200 mg/dl) | 212.0 ± 6.7 | 204.0 ± 6.0 |
CK (normal values: male < 190 mg/dl, female < 125 mg/dl) | Male: 280 ± 3.5 | Male: 128.8 ± 27.2 |
Female: 224.6 ± 22.7 | Female: 124.5 ± 24.1 | |
Arrhythmia (% of patients) | 38 | 0 |
Cataract (% of patients) | 56 | 0 |
ECG-QRS duration (normal values: 60–110 ms) | 103.5 ± 4.3 | NA |
Number of CTG repeats (range) | 484.0 ± 27.6 (65–1400) | NA |
Stage of disease (range 1–5) (% of patients at each stage) | Stage 1: 5 | NR |
Stage 2: 29 | ||
Stage 3: 34 | ||
Stage 4: 28 | ||
Stage 5: 3 |
