Figure 2
From: The defining DNA methylation signature of Floating-Harbor Syndrome
DNA methylation profiles in FHS.
Methylation level from 0 (not methylated) to 1 (100% methylated) is shown across regions with significantly altered methylation in FHS: hypermethylated regions (a) MYO1F and (b) RASIP1; and hypomethylated regions (c) FIGN and (d) STPG2. RefSeq genes and CpG islands tracks are annotated on top of the figures. The top image corresponds to methylation array data visualized using Genomic Browser Viewer (Partek). Red lines correspond to representative control sample data. Blue lines correspond to FHS individual data. The bottom image corresponds to average methylation based on bisulfite sequencing data. The red and blue lines indicate the average methylation for control and FHS patient sample, respectively. Dotted lines correlate chromosome location between top (array generated) and bottom (bisulfite sequence generated) images.
