Figure 5
From: Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney
Urinary iron, protein content and H&E, PAS staining in the renal medulla and cortex.
Total iron content in the urine of WT, Heph/Cp KO, Cp KO, and Heph KO mice was measured and total urine iron content was normalized to urine CR (A). Total protein concentration of WT, Heph/Cp KO, Cp KO, and Heph KO mice was measured and normalized to the urinary CR (B). Values are means ± SEM, n = 10 mice per group. Within each panel, bars without common letters are significantly different, P < 0.05. Representative photomicrographs of H&E and PAS staining for the tissues of renal medulla (C,E) and renal cortex (D,F) in WT, Heph/Cp KO, Cp KO, and Heph KO mice. The images were taken at high power (400×) and oil (1000×) lens.
