Table 2 MIC of the peptides against the selected bacteria.

From: Antimicrobial and anti-inflammatory activities of three chensinin-1 peptides containing mutation of glycine and histidine residues

Microorganism

MIC(μM) a

MC1-1

MC1-2

MC1-3

G−

 E. coli

6.25

3.13

6.25

 P. aeruginosa

3.13

1.56

6.25

 GM (μM) b

4.42

2.21

6.25

G+

 S. aureus

6.25

3.13

6.25

 B. cereus

3.13

3.13

6.25

 S. lactis

6.25

6.25

12.5

 E. faecalis

1.56

1.56

6.25

 E. faecium

3.13

1.56

6.25

 GM (μM)

3.59

2.72

7.18

 HC50 (μM)

>500

 
  1. aMinimum inhibitory concentration (MIC) was determined as the lowest concentration of the peptide that inhibited growth. Data are representative of three independent experiments.
  2. bThe geometric mean (GM) of the peptide MICs against the bacteria was calculated.
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