Table 4 Thermodynamic parameters of the interactions of the mutated peptides with LPS.

From: Antimicrobial and anti-inflammatory activities of three chensinin-1 peptides containing mutation of glycine and histidine residues

 

MC1-1

MC1-2

MC1-3

N

0.83 ± 0.02

1.75 ± 0.01

0.66 ± 0.03

Ka (mM−1)

99.8 ± 10

99.8 ± 4.3

96.7 ± 11.7

ΔH (kcal.mol−1)

−39.8 ± 1.5

−7.3 ± 0.1

−62.4 ± 3.4

ΔS (kcal.mol−1deg−1)

−0.0325

−0.0007

−0.106

ΔG (kcal.mol−1)

−29.7

−7.1

−29.6

Kd (μM)

10.0 ± 1

10.0 ± 0.4

10.5 ± 1.2

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