Figure 3: TNTs serve as a conduit for intracellular transport of IAV proteins.
From: Influenza virus exploits tunneling nanotubes for cell-to-cell spread
Fluorescent images showing accumulation of influenza virus proteins NP, HA, M, and M1 proteins within TNTs. A population of A549 cells was infected with PR8 virus for 18 h, trypsinized and seeded on glass-bottom plates for 2 h after which they were imaged as described in materials and methods. Viral proteins are observed in the membrane nanotubes.
