Figure 8: NO dependent systemic IR in iNOS KO mice. | Scientific Reports

Figure 8: NO dependent systemic IR in iNOS KO mice.

From: Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance

Figure 8

Total nitrite levels in (a) Plasma and (b) metabolic tissues (liver, adipose tissue and skeletal muscle) (n = 5), qPCR expressions of (c) eNOS, nNOS and (g) UCP2 (n = 6), (d,e) hepatic mitochondrial OCR (n = 3), and (f) tissue ATP (n = 5) in 5 weeks LFD fed WT and iNOS KO mice. Comparison between groups was done by Student’s t test except qPCR studies where Mann-Whitney U test was applied. *p < 0.05 an **p < 0.01 vs WT.

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