Table 1 Biochemical parameters in 5 weeks LFD fed WT and KO mice.

From: Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance

S. No.

Parameter

5 weeks

6 h fasted

Overnight fasted

Fed (ad libitum)

WT

KO

WT

KO

WT

KO

1

TG (mg/dl)

81.55 ± 3.35

178.37 ± 6.96***

79.42 ± 7.07

238.29 ± 32.25***

104.26 ± 8.10

151.09 ± 9.03**

2

TC (mg/dl)

99.22 ± 3.59

175.87 ± 6.38***

82.51 ± 6.69

256.09 ± 17.55***

133.92 ± 7.67

178.08 ± 15.55*

3

LDL (mg/dl)

22.71 ± 1.70

25.36 ± 2.21

44.31 ± 3.25

56.19 ± 7.38

17.54 ± 1.43

18.95 ± 1.11

4

HDL (mg/dl)

34.45 ± 2.93

32.66 ± 2.34

43.72 ± 3.11

51.27 ± 6.43

23.14 ± 1.37

26.94 ± 1.70

5

NEFA (mmol/L)

0.92 ± 0.04

1.69 ± 0.07***

1.45 ± 0.14

3.25 ± 0.11***

0.74 ± 0.04

1.00 ± 0.09*

6

Glucose (mg/dl)

142.13 ± 2.41

166.38 ± 5.61**

112.75 ± 5.36

126.63 ± 5.07

182.88 ± 4.82

197.38 ± 7.01

7

Insulin (ng/ml)

0. 69 ± 0.03

1.08 ± 0.13*

0.43 ± 0.03

0.54 ± 0.05

1.49 ± 0.06

3.40 ± 0.48**

8

HOMA-IR

—

—

2.62 ± 0.22

3.79 ± 0.49*

—

—

9

HOMA-B

—

—

75.96 ± 10.34

68.35 ± 5.53

—

—

10

QUICKI

—

—

0.33 ± 0.0038

0.32 ± 0.0054*

—

—

11

ALT (IU/L)

31.55 ± 2.11

27.20 ± 0.97

31.78 ± 3.19

27.21 ± 1.88

36.53 ± 4.65

27.09 ± 2.29

12

T. Bilirubin (mg/dl)

0.13 ± 0.02

0.11 ± 0.02

0.15 ± 0.01

0.14 ± 0.02

0.16 ± 0.01

0.17 ± 0.01

13

Creatinine (mg/dl)

0.29 ± 0.01

0.24 ± 0.03

0.32 ± 0.02

0.30 ± 0.02

0.28 ± 0.01

0.26 ± 0.01

  1. Results are expressed as mean ± SEM (n = 8–10).
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