Figure 2: Chrysophanol preserved MNU-injured photoreceptor function on day 7. | Scientific Reports

Figure 2: Chrysophanol preserved MNU-injured photoreceptor function on day 7.

From: The natural retinoprotectant chrysophanol attenuated photoreceptor cell apoptosis in an N-methyl-N-nitrosourea-induced mouse model of retinal degenaration

Figure 2

(a) Representative scotopic ERG responses from control mice (blue curve), and MNU-exposed mice treated with the vehicle control (red curve) or chrysophanol (green curve). (b,c) Quantification of the average amplitudes and implicit time (time to peak) from control mice (n = 7), and MNU-exposed mice treated with the vehicle control (n = 5) or chrysophanol (n = 11). The ERG a-waves were negative, and the a-wave amplitudes are presented as the absolute value. The data were presented as the mean ± SEM. CTRL: control. #p < 0.05 compared with the control group treated with vehicle, ##p < 0.001 compared with the control group treated with vehicle, *p < 0.01 compared with MNU-exposed group treated with vehicle.

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