Figure 5: Chrysophanol significantly reduced MNU-induced photoreceptor cell death on day 1. | Scientific Reports

Figure 5: Chrysophanol significantly reduced MNU-induced photoreceptor cell death on day 1.

From: The natural retinoprotectant chrysophanol attenuated photoreceptor cell apoptosis in an N-methyl-N-nitrosourea-induced mouse model of retinal degenaration

Figure 5

(a) The time course of retinal cell death after MNU (60 mg/kg) administration as determined by TUNEL-labeling (green dot). The number of apoptotic cells peaked 1 day after the administration of MNU. (b) TUNEL-stained sections revealing dead photoreceptors in DAPI-counterstained retinal sections. CTRL: control; GCL: ganglion cell layer; INL: inner nuclear layer; ONL: outer nuclear layer.

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