Figure 8: Proteins involved in ROS generation and elimination as a response to hypoxia in P. umbellatus. | Scientific Reports

Figure 8: Proteins involved in ROS generation and elimination as a response to hypoxia in P. umbellatus.

From: SWATH label-free proteomics analyses revealed the roles of oxidative stress and antioxidant defensing system in sclerotia formation of Polyporus umbellatus

Figure 8

This schematic diagram was composed of electron transfer chain, TCA cycle and glycolysis. The expression of SDH subunits of complex II and IDH in TCA cycle was decreased in P. umbellatus sclerotia at initial phase leading to the increased ratio of NAD(P)+/NAD(P)H and ROS accumulation. NAD(P)H required for GSH to eliminate ROS could be accumulated with elevated alcohol dehydrogenase and aldehyde dehydrogenase following glycolysis/gluconeogenesis activation.

Back to article page