Table 1 Comparison of baseline demographics between patients with neovascular Age-related Macular Degeneration (nAMD) and age and gender matched controls.

From: Systemic, Ocular and Genetic Risk Factors for Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Singaporeans

 

Controls (N = 1824)

nAMD (N = 456)

P value

Age (years), Mean (SD)

64.4 (8.53)

69.4 (9.36)

<0.001

Gender, male (%)

62.7

62.5

0.931

Race

  

0.936

Chinese (%)

93.2

93.2

 

Malay (%)

5.0

4.82

 

Indian (%)

1.8

1.97

 

Presenting Vision ± SD (LogMAR)

0.33 (0.33)

0.87 (0.63)

<0.001

BMI ± SD (kg/m2), Mean (SD)

23.9 (3.67)

24.4 (4.04)

0.012

Hypertension (%)

70.3

71.9

0.496

Creatinine ± SD (mmol/L), Mean (SD)

82.63 (45.6)

83.25 (32.9)

0.799

Smoking status

  

0.003

Nonsmoker (%)

66.4

58.1

 

Past smoker (%)

17.9

24.3

 

Current smoker (%)

15.7

17.6

 

Cardiovascular Disease (%)

10.1%

13.6%

0.039

Stroke (%)

3.18%

5.04

0.069

Diabetes (%)

39.6

38.7

0.730

Glucose ± SD (mmol/L)

6.63 (3.03)

6.57 (2.29)

0.836

Hba1c ± SD (%)

6.14 (0.98)

6.09 (0.86)

0.306

Total Cholesterol ± SD (mmol/L)

5.37 (1.10)

5.09 (1.11)

<0.001

LDL-cholesterol ± SD (mmol/L)

3.22 (0.92)

3.09 (0.91)

0.048

HDL-cholesterol ± SD (mmol/L)

1.27 (0.39)

1.38 (0.41)

<0.001

Axial Length ± SD (mm)

23.94 (1.41)

23.53 (1.74)

<0.001

Pseudophakia (%)

14.2

28.3

<0.001

  1. SD standard deviation; BMI body mass index; LDL-cholesterol Low density Lipoprotein- cholesterol; HDL-cholesterol High density Lipoprotein cholesterol.
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