Figure 6: 90Sr exposure modifies cellular functions.

(a) Number of CFCs per 20,000 cells after 12 days of culture with conditioned medium in methylcellulose medium without growth factors (one-way ANOVA, F(4, 65) = 2.523, *p < 0.05) or supplemented with erythropoietin ( + EPO, one-way ANOVA, F(4, 65) = 3.685, **p < 0.001). Abbreviations: Sn, Supernatant; EPO: Erythropoietin. (b) Concentration of IL-6, SCF and G-CSF (pg.mL−1) in cell supernatants after 7 days of exposure to 90Sr (one-way ANOVA, n.s.). GM-CSF and IL-3 concentrations were below the detection limit. (c) Number of CFCs per 105 cells obtained by the LTC-IC assay (one-way ANOVA, n.s.).