Figure 5: Identification of the CRC proteomic signature. Heat map depicting the relative abundance of ranked proteins (fold change >4, pā<ā0.01) identified across 44 samples (22 CRC and 22 AT).

Twenty-two tumors and 22 AT samples are displayed as columns, and proteins are displayed as rows. The color key indicates the relative abundance of proteins (0 to 1.0) across 44 samples. The heat map presents the differential expression of (A) 715 CRC protein signatures across 44 samples, (B) 567 proteins (listed in Sadanandam 786 CRC assigner) identified across 44 samples, (C) 102 proteins (listed in Melo CCSs 146 gene classifier) identified across 44 samples, and (D) 100 proteins (listed in Vogelstein 125 tumor driver genes) identified across 44 samples. The details of the data is in Dataset 6.